BackgroundTyphoid fever is a common cause of febrile illness in low- and middle-income countries.While multidrug-resistant (MDR) Salmonella Typhi (S.Typhi) has spread globally, fluoroquinolone resistance has mainly affected Asia.MethodsConsecutively, 1038 blood cultures were obtained from patients of all age groups with fever and/or suspicion of se
In grapheme-color synesthesia, letters and numbers evoke abnormal colored perceptions.Although the underlying mechanisms are not known, it is largely thought that the synesthetic brain is characterized by atypical connectivity throughout various brain regions, including the visual areas.To study the putative impact of synesthesia on the visual brai
Abstract Background Microsatellite instability (MSI) due to mismatch repair deficiency (dMMR) is common in colorectal cancer (CRC).These cancers are associated with somatic coding events, but the noncoding pathophysiological impact of this genomic instability is yet poorly understood.Here, we perform an analysis of coding and noncoding MSI events a
Myopic traction maculopathy (MTM) Agogo Bell affects 20% of eyes with pathologic myopia (PM).The MTM Staging System (MSS), published in 2020, describes the nomenclature of MTM as well as a proposal of pathogenesis, natural evolution, and prognosis.A study of customized treatment for each stage of MTM has been published previously and suggested to t